Hippocampus, the part of brain, has been considered as the hub of memory, but now researches have founded the mechanism of storage and recall of the image in this part of brain.

Scientist of the welcome trust makes four patients to recognize several virtual reality atmospheres. Then distinct pattern of brain activity expressed where they were, scientist reported in the journal.

Place cells or neurons of hippocampus activate to tell us the exact location and place where we move. The team of researchers then used the modern scanning instruments which calculated the blood flow towards brain.

While playing video games, researchers manipulated the data of participants in the computer when they were moving around in the virtual reality.

Astonishingly we pin pointed the location of virtual reality environment in the brain, means we red the spatial memory.

By analyzing the millions of neuron, we concluded that there must be a functional function that encodes the memories. The volunteers take deep interest and prepared there brain that ease the process of monitoring of brain.

“By understanding the mechanism of memory storage we can help patients with compromised memory in the process of rehabilitation,” said Professor Maguire.

These findings will enhance our understandings of the hippocampus, a vital area that is affected by the Alzheimer’s disease and the essential part of brain in terms of memory. Exploring the complications of brain’s work will provide us the opportunity to find what kind of nerve cells are being damaged by the Alzheimer’s

Prions, the cellular proteins, initiate the reaction through which amyloid-beta peptides harm the functioning of the brain of Alzheimer’s patient.

“The researchers know that, amyloid-beta peptides causes harm to brain but their exact worse action on the neurons is still unknown,” Study author Stephen M. Strittmatter said.

After assessing number of potential disease-mediating receptors, researchers found the culprit prion protein that worse the condition of Alzheimer’s disease. Prion used to attach with the amyloid-beta peptides and damage the brain cells. They start the drop of neuron that makes the condition more serious, researchers added.

Cellular prion protein is a commonly occurring form of protein and almost available in all cells. These are harmless proteins but in certain conditions or in the presence of the other compounds, these can change their structure and cause diseases.

Because the involvement of these proteins has been seen in the initial stages of the disease that is why, these can be selected as an important target for the new treatments of the Alzheimer.

This particular study does not prove that prion cellular proteins convert into any infectious or toxic agent in the disease, but the results suggest the role of these nontoxic proteins in the Alzheimer and neurodegenerative disease necessitates further studies.

These are the conclusive findings of a recent study carried out at the “University of Pitsbugh”.These findings were also presented recently at the annual meeting of the” Radiological Society of North America(RSNA)”.There have been several researches in recent past and there are enough evidences available that connect the cardiovascular health with the brain health.

Reliable estimations of the “National Heart, Lung and Blood Institute” reveal that there are almost 50 million Americans who are suffering from hypertension presently. All these people are open to direct risks of cardiac attacks and aneurysm. Mild cognitive impairment, which affects brain functions such as language, attention and reasoning, is a transition stage between normal aging deficits in the brain and greater levels of dementia.

This study demonstrates that good vascular health is equally good for the brain.“Even in people with Alzheimer’s disease, it is important to detect and aggressively treat hypertension and also to focus on disease prevention”, said Dr.Oscar Lopez, Professor of Neurology and Psychiatry at the University of Pittsburgh.

Researchers applied specific techniques and used ‘arterial spin-labeled magnetic resonance imaging (MRI)’. For 68 older adults, this technique was applied for measuring and imaging the blood flow in the brain.’ Arterial Spin-Labeled Magnetic Resonance Imaging (MRI)’ is a novel, non-invasive technique and it does not require any external contrast agent.

The study involved 48 normal individuals. This group of individuals included 38 with hypertension and 10 without; 20 Alzheimer’s patients, including 10 with hypertension and 10 without; and 20 adults with mild cognitive impairment, 10 with hypertension and 10 without.

The MRI results thus obtained showed that in all patient groups blood flow in the brain was substantially decreased in patients with hypertension compared to those individuals who did not have hypertension. Cerebral blood flow recorded came out to be the lowest among the Alzheimer’s patients with hypertension, but the normal group with hypertension showed significantly lower cerebral blood flow in comparison to the normal group having no hypertension.

The study results established that a positive change in the blood flow patterns will make impacts on the hypertension and would be helpful in contributing to the pathology of Alzheimer’s disease.

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