Researchers of Yale University said, the missing link, vital for the better understanding of Alzheimer’s disease, have been founded by them.

Prions, the cellular proteins, initiate the reaction through which amyloid-beta peptides harm the functioning of the brain of Alzheimer’s patient.

“The researchers know that, amyloid-beta peptides causes harm to brain but their exact worse action on the neurons is still unknown,” Study author Stephen M. Strittmatter said.

After assessing number of potential disease-mediating receptors, researchers found the culprit prion protein that worse the condition of Alzheimer’s disease. Prion used to attach with the amyloid-beta peptides and damage the brain cells. They start the drop of neuron that makes the condition more serious, researchers added.

Cellular prion protein is a commonly occurring form of protein and almost available in all cells. These are harmless proteins but in certain conditions or in the presence of the other compounds, these can change their structure and cause diseases.

Because the involvement of these proteins has been seen in the initial stages of the disease that is why, these can be selected as an important target for the new treatments of the Alzheimer.

This particular study does not prove that prion cellular proteins convert into any infectious or toxic agent in the disease, but the results suggest the role of these nontoxic proteins in the Alzheimer and neurodegenerative disease necessitates further studies.