Aspirin may neutralize the adverse effect of paracetamol or excessive drinking to save liver, researches said.
The Yale University team, founds that use of aspirin can reduce the death risk in mice given a paracetamol overdose.
The phenomenon behind, it intercepts the chemical pathway that initiate inflammation within the organ. However the use of aspirin for this purpose in human is not known.
Cases of liver cirrhosis are rising day by day in the UK. The major reason behind is the extensive use of alcohol or the paracetamol overdose that contribute to more than hundred death per year.
Scientists are trying to find out the reason of liver damage due to paracetamol and alcohol. They also working on the start of chain reaction, triggered after the onset of inflammation caused by these two chemicals. The inflammation represents the high degree of liver damage.
In this latest research, scientists found that the death rate can be minimized in the mice being given with high dose of paracetamol, if a small dose of aspirin is also given.
The researchers believe that aspirin blocks the chemical receptors of liver that stimulate the inflammatory response.
Scientist have separated specific molecules called tool-like receptors antagonists, which can also block the receptors of liver, but aspirin is far cheaper than the isolated chemical that make it a useful therapy.
“Nothing till to date has been clinically proven to protect the liver from alcohol abuse. We also recommend that you should consult your doctor first for the long term use of aspirin.”
NHS Direct warns that, long term use of aspirin, without precaution can cause irritate inner walls of the stomach and a higher risk of bleeding and ulceration.




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